Clinical Cases
Clinical Case Analysis – Oral Squamous Papilloma (HPV)
Early detection can make the difference
The Human Papillomavirus (HPV) can affect different areas of the body, including the oral cavity. However, there is very little information available about its manifestations in the mouth, which is why we believe it is important to discuss the topic and encourage early evaluation.
This clinical case documents the diagnosis and treatment of a benign lesion known as Oral Squamous Papilloma, highlighting the importance of professional examination and timely care.
Implante dental con regeneración ósea guiada
La implantología moderna permite reemplazar piezas dentales perdidas de forma segura, estética y duradera.
En este caso clínico, el Dr. Marco C. Moreno —cirujano oral y especialista en implantología— comparte el proceso completo de colocación de un implante con regeneración ósea guiada, desde el diagnóstico hasta el resultado final.
Clinical Cases
Clinical Case Analysis – Oral Squamous Papilloma (HPV)
Early detection can make the difference
The Human Papillomavirus (HPV) can affect different areas of the body, including the oral cavity. However, there is very little information available about its manifestations in the mouth, which is why we believe it is important to discuss the topic and encourage early evaluation.
This clinical case documents the diagnosis and treatment of a benign lesion known as Oral Squamous Papilloma, highlighting the importance of professional examination and timely care.
What Is Oral Squamous Papilloma?
Oral squamous papilloma is a benign lesion of the oral mucosa caused by the Human Papillomavirus (HPV), typically by types 6 and 11, classified as low-risk strains.
It appears most frequently in young adults and commonly affects the tongue, palate, or inner cheek mucosa.
Symptoms and detection:
- Appearance of small white or pink growths or nodules.
- Usually painless, though they may enlarge or become irritated from friction.
- Often detected during routine dental or oral examinations.
Why diagnosis matters: Although benign, the lesion must be evaluated by a certified oral surgeon to rule out precancerous changes and determine the correct treatment approach.
What Is Oral Squamous Papilloma?
Oral squamous papilloma is a benign lesion of the oral mucosa caused by the Human Papillomavirus (HPV), typically by types 6 and 11, classified as low-risk strains.
It appears most frequently in young adults and commonly affects the tongue, palate, or inner cheek mucosa.
Symptoms and detection:
- Appearance of small white or pink growths or nodules.
- Usually painless, though they may enlarge or become irritated from friction.
- Often detected during routine dental or oral examinations.
Why diagnosis matters: Although benign, the lesion must be evaluated by a certified oral surgeon to rule out precancerous changes and determine the correct treatment approach.
Dr. Marco C.
Moreno Rojo
Certified Oral Surgeon | University Professor | Implantology Specialist
Dr. Marco Moreno Rojo is a certified oral surgeon with over a decade of experience in oral surgery and implantology.
His education, commitment, and trajectory make him a regional reference, combining clinical practice with university teaching at the Autonomous University of Baja California (UABC) since 2018, where he also earned his professional degree.
Currently, Dr. Moreno Rojo is part of the exclusive group of certified oral surgeons in Baja California, being one of only four specialists officially recognized by national certification boards in this dental specialty.
Dr. Marco Moreno
Certified Oral Surgeon | University Professor | Implantology Specialist
Dr. Marco Moreno Rojo is a certified oral surgeon with over a decade of experience in oral surgery and implantology.
His education, commitment, and trajectory make him a regional reference, combining clinical practice with university teaching at the Autonomous University of Baja California (UABC) since 2018, where he also earned his professional degree.
Currently, Dr. Moreno Rojo is part of the exclusive group of certified oral surgeons in Baja California, being one of only four specialists officially recognized by national certification boards in this dental specialty.
Microscopic Findings
The histopathological analysis revealed proliferation of stratified squamous epithelium with finger-like projections typical of squamous papillomas.
The study identified:
- Koilocytes: epithelial cells altered by viral infection.
- Acanthosis and edema: epithelial thickening and mild inflammation.
- Collagen fibers and blood vessels in the stroma, with foci of recent hemorrhage.
These findings confirmed a benign viral-related lesion with no evidence of malignancy.
Microscopic Findings
The histopathological analysis revealed proliferation of stratified squamous epithelium with finger-like projections typical of squamous papillomas.
The study identified:
- Koilocytes: epithelial cells altered by viral infection.
- Acanthosis and edema: epithelial thickening and mild inflammation.
- Collagen fibers and blood vessels in the stroma, with foci of recent hemorrhage.
These findings confirmed a benign viral-related lesion with no evidence of malignancy.
Diagnosis and Treatment
The final diagnosis was Oral Squamous Papilloma associated with low-risk HPV (types 6 and 11).
Treatment consisted of complete surgical excision of the lesion, followed by postoperative control and clinical follow-up.
After healing, the patient showed excellent recovery and no recurrence during subsequent check-ups.
Diagnosis and Treatment
The final diagnosis was Oral Squamous Papilloma associated with low-risk HPV (types 6 and 11).
Treatment consisted of complete surgical excision of the lesion, followed by postoperative control and clinical follow-up.
After healing, the patient showed excellent recovery and no recurrence during subsequent check-ups.
Importance of Clinical Follow-Up
Although oral squamous papilloma is a benign lesion, periodic professional supervision is essential to ensure favorable healing and to detect possible recurrence early.
In some cases, lesions may regress spontaneously, but specialized monitoring and, when needed, surgical removal remain the safest approach.
📞 Schedule Your Evaluation
Have you noticed a lesion or change in your tongue or gums?
Early diagnosis can make all the difference.
Schedule your consultation with Dr. Marco Moreno, Certified Oral Surgeon in Tijuana.
📲 WhatsApp or Call:
(619) 432-0502
(664) 977-5558
🌐 www.dentalcorptj.com
Importance of Clinical Follow-Up
Although oral squamous papilloma is a benign lesion, periodic professional supervision is essential to ensure favorable healing and to detect possible recurrence early.
In some cases, lesions may regress spontaneously, but specialized monitoring and, when needed, surgical removal remain the safest approach.
📞 Schedule Your Evaluation
Have you noticed a lesion or change in your tongue or gums? Early diagnosis can make all the difference.
Schedule your consultation with Dr. Marco Moreno, Certified Oral Surgeon in Tijuana.
📲 WhatsApp or Call: (619) 432-0502 | (664) 977-5558
🌐 www.dentalcorptj.com





